Methionine. Inositol. Choline. Cyanocobalamin.
A compounded lipotropic injection that supports fat metabolism and liver function.
Often stacked with GLP-1 for patients focused on body composition.
Provider-prescribed. 503B pharmacy compounded. Delivered monthly.
Results vary. MICC is not a standalone weight loss treatment. Provider evaluation required before prescription is issued. If approved, compounded by a licensed 503B pharmacy.
MICC is a compounded lipotropic injection — four ingredients, each with a distinct biological role in fat metabolism and liver function. This isn't a proprietary blend or a wellness trend. It's a straightforward formulation with decades of clinical use, delivered subcutaneously on a weekly or bi-weekly schedule.
The name is an acronym: Methionine, Inositol, Choline, Cyanocobalamin (B12). Each compound works through a different pathway. Together, they support the liver's capacity to process and export dietary fat — a function that becomes limiting under caloric restriction, metabolic stress, or GLP-1 protocols.
AnthologyRX prescribes MICC after provider evaluation. Your intake is reviewed by a licensed physician who confirms candidacy, reviews your current medications, and determines an appropriate dosing schedule. If approved, your compounded MICC is dispensed from a licensed 503B pharmacy and delivered monthly. Results vary.
Not a supplement.
Not a med spa lipo shot.
A clinical formulation prescribed by a physician.
Compounded by a licensed 503B pharmacy.
Delivered monthly.
Managed around your protocol.
The most affordable protocol in the lineup — designed as a lean, effective add-on for patients already optimizing body composition. If approved, $99/mo all-in.
Each letter in MICC represents a distinct compound. Your provider prescribes the full formulation — here's what each one does and why it's included.
Methionine is an essential amino acid — the body cannot synthesize it, so it must come from diet or supplementation. It plays a central role in fat breakdown and liver detoxification. In the liver, methionine participates in the methylation cycle, which supports the conversion of fats into exportable lipoproteins. Without adequate methionine, fat can accumulate in the liver — a process accelerated during aggressive caloric restriction. It also contributes to glutathione synthesis, the body's primary antioxidant defense. In the MICC formulation, methionine is the foundational lipotropic agent.
Inositol is a carbocyclic sugar that functions as a secondary messenger in insulin signaling. It supports the liver's ability to regulate fat metabolism by facilitating the breakdown of lipids and improving insulin sensitivity at the cellular level. Clinically, inositol has been studied for its effects on metabolic syndrome, PCOS, and fat cell responsiveness. In the context of MICC, its primary role is to enhance the metabolic conditions under which the other lipotropic compounds operate — specifically by improving how fat cells respond to hormonal signals and how efficiently the liver processes stored triglycerides. Inositol also has a documented relationship with serotonin receptor function, which may contribute to mood stability during caloric restriction.
Choline is an essential nutrient required for the synthesis of phosphatidylcholine — the primary phospholipid in cell membranes and the structural backbone of very-low-density lipoproteins (VLDL). VLDL is the transport vehicle the liver uses to export fat into circulation. Without sufficient choline, the liver cannot package and export dietary fats efficiently, leading to hepatic fat accumulation (non-alcoholic fatty liver). During GLP-1 protocols or any significant caloric restriction, choline demand increases as the liver is required to process higher volumes of mobilized fat. Choline also supports neurological function — it's a precursor to acetylcholine, the neurotransmitter involved in memory and muscle control. Deficiency is common in the general population and compounded in high-output individuals.
Cyanocobalamin is the synthetic, stable form of vitamin B12 — the most commonly used form in compounded injectables due to its shelf stability. B12 is essential to the methylation cycle, which methionine also participates in, creating a synergistic relationship between the two in the MICC formula. It supports red blood cell formation, neurological function, and energy metabolism. Subcutaneous delivery of cyanocobalamin bypasses the GI absorption pathway — particularly important for individuals with suboptimal B12 status due to dietary habits, medication interactions (metformin suppresses B12 absorption), or age-related decline in intrinsic factor. Many patients on GLP-1 protocols notice improved energy and mood stabilization as a downstream effect of restored B12 status. Results vary.
Methionine and choline work together to support the liver's ability to process and export dietary and stored fat. Choline enables VLDL synthesis — the packaging mechanism for fat export — while methionine drives the methylation reactions that keep this cycle running. The result: a liver that can handle the fat mobilization demands of an active caloric deficit without accumulating hepatic fat.
During GLP-1 protocols or any significant caloric restriction, the liver is called upon to process higher volumes of mobilized fat. MICC's lipotropic compounds — specifically choline and methionine — reduce hepatic fat accumulation and support the liver's detoxification capacity. For patients stacking MICC with GLP-1, this is the most clinically relevant benefit: protecting liver function during a period of rapid body composition change. Provider evaluation required.
Inositol supports glucose regulation and fat cell responsiveness to insulin signaling. In the context of body composition protocols, this translates to improved partitioning — the body's ability to direct nutrients appropriately rather than defaulting to fat storage. For individuals with metabolic resistance, impaired insulin sensitivity is often the rate-limiting factor. Inositol addresses this at the receptor level. Results vary by individual metabolic status.
Cyanocobalamin (B12) supports neurological function, mitochondrial energy production, and mood stability — all of which are commonly affected during caloric restriction. Subcutaneous delivery bypasses GI absorption, making it particularly effective for individuals who supplement orally with limited success. Many patients on MICC report improved energy within the first few weeks, with mood stabilization following as B12 status normalizes. Results vary.
You're already on a GLP-1 protocol and you're getting results — but you want to optimize how and where you're losing. MICC is the most commonly stacked add-on for GLP-1 patients focused on body composition. Your provider evaluates compatibility and dosing schedule during your intake review.
Your diet is clean, your training is consistent, but body composition changes come slowly and hepatic fat markers have flagged in past labs. MICC's lipotropic compounds address the liver-side bottleneck that dietary intervention alone can't fully resolve. Results vary. Provider evaluation required.
You're looking for an affordable, evidence-informed add-on to an existing protocol. At $99/mo, MICC is the lowest-priced option in the AnthologyRX lineup — and one of the most complementary across multiple treatment categories. No need to overhaul your current regimen. If approved, it slots in alongside what you're already doing.
Your intake screens for all relevant contraindications. A licensed physician reviews every submission before any prescription is issued. If your profile presents any borderline factors, your provider will communicate directly — no guesswork, no automatic approvals. Results vary.
A structured medical questionnaire covering your health history, current medications, active protocols, and body composition goals. Under five minutes. No video call. No waiting room. Completed entirely on your schedule — provider evaluation follows.
A licensed physician reviews your intake within 48 hours. They evaluate candidacy, confirm no contraindications, assess compatibility with any existing protocols, and issue your prescription if approved. If not approved, you're notified immediately with clinical reasoning — no charge.
Your compounded MICC ships from a licensed 503B outsourcing facility — temperature-controlled packaging, tracked delivery, direct to your door on the recurring protocol schedule. Injection supplies are included. No pharmacy visit. No insurance required.
Provider check-ins, dosing adjustments based on your response, and direct messaging access to your care team. If you're stacking MICC with another AnthologyRX protocol, your care team coordinates across both. Your protocol evolves with your progress.
I added MICC to my GLP-1 protocol three months ago. The difference in how I'm losing — where I'm losing — is noticeable. Less bloating, tighter midsection. I'm not saying it's magic. I'm saying the combination is doing something my GLP-1 alone wasn't.
Honestly, I started this skeptically. But $99/mo to try something with real lipotropic science behind it? Easy decision. That was nine months ago. My energy baseline is up, my labs look better, and I haven't stopped. Some things you just keep doing because they work.
I know the biochemistry and I know what MICC does — it's not magic, but it's mechanistically real. I recommend it to patients who are already on GLP-1. The liver support during rapid fat mobilization is the part most people don't think about. It complements well.
Individual results vary and are not typical. Testimonials reflect patient-reported outcomes and are used as illustrations only. MICC is not a standalone weight loss treatment. Results are not guaranteed. All patients are under licensed physician supervision. If approved by a provider.
Subscriptions renew monthly. Cancel anytime before your renewal date — no fees, no calls required. Provider review is required before any prescription is issued. All treatments require physician approval. MICC is not a standalone weight loss treatment. Results vary. FSA/HSA eligibility depends on your individual plan.
The same compounds — yes. The clinical context — entirely different. Med spa "lipo shots" are often administered by aesthetic technicians without a prior physician evaluation, use variable compounding sources, and lack ongoing medical management. AnthologyRX prescribes MICC only after a licensed physician reviews your intake, confirms candidacy, and evaluates compatibility with your existing medications and protocols. Your compounded MICC comes from a licensed 503B outsourcing facility operating under federal cGMP standards — not a retail compounding pharmacy. The formulation is the same. The oversight is not.
Most patients administer MICC weekly or bi-weekly via subcutaneous injection — typically in the abdomen, thigh, or upper arm. Your prescribing physician will specify your exact schedule based on your clinical profile and any other protocols you're on. Injection supplies are included with your monthly shipment. If you've never self-injected before, detailed instructions and video support are provided through your patient portal. Most patients report the process becomes routine within the first two injections.
Yes. MICC is commonly stacked with GLP-1, but it is not exclusive to GLP-1 patients. Candidates include adults with sluggish fat metabolism, individuals with elevated hepatic fat markers, those with confirmed B12 insufficiency, and anyone looking for an affordable, evidence-informed lipotropic support protocol. Your physician evaluates candidacy based on your individual profile — not a predefined stack. If approved, MICC stands on its own as a meaningful metabolic support tool. Results vary.
MICC is generally well-tolerated. The most commonly reported effects are mild injection-site reactions — redness, tenderness, or mild swelling at the injection site — which typically resolve within 24 hours. Some patients report a temporary metallic taste following injection, particularly associated with the cyanocobalamin component; this is benign and resolves quickly. Nausea is uncommon but reported in some patients, particularly early in the protocol. Serious adverse events are rare. If you experience any unexpected or persistent effects, your care team is available via direct messaging. Your provider reviews your full medication list and health history before prescribing — drug interactions are evaluated at intake.
Results vary significantly by individual and depend on your starting metabolic status, diet, activity level, and whether MICC is part of a broader protocol. Many patients report improved energy and reduced fatigue within the first two to four weeks — often the earliest signal of improved B12 status. Body composition changes are more gradual and typically become noticeable at six to twelve weeks when MICC is combined with appropriate caloric management or a GLP-1 protocol. MICC is a metabolic support tool, not a primary weight loss intervention. It works best as part of a coordinated protocol, not in isolation. Results are not guaranteed.
Potentially yes. FSA/HSA eligibility for compounded prescription medications depends on your specific plan's rules and whether the medication is prescribed for a qualifying medical condition. AnthologyRX automatically generates a detailed receipt for every transaction, including the prescribing physician's information and the compound name — the documentation your plan administrator will need to evaluate your claim. We recommend confirming eligibility with your FSA/HSA plan administrator before assuming coverage. Our support team can provide additional documentation if required by your plan.
Your assessment takes five minutes. Provider review within 48 hours. If approved, $99/mo — all-inclusive, no hidden fees, cancel anytime.
